Excerpted from my dermpath board review video (https://youtu.be/Q88yDU-Pyis) for my 5-Minute Pathology Pearls video series. See also my full AFX video showin

Atypical fibroxanthoma prognosis Atypical fibroxanthoma rarely recurs after complete excision with clear margins. Recurrence and metastasis are more likely in people that are immunosuppressed. Fortunately, atypical fibroxanthoma rarely metastasizes and recurs in only 6% to 10% of cases 6).

Leiomyosarcoma : Usually positive for smooth muscle markers, such as smooth muscle myosin and desmin. Metastatic carcinoma : I’m sorry to hear that you’ve been recently diagnosed with Atypical Fibroxanthoma (AFx) in addition to lung cancer. Here is a short video of Mayo Clinic dermatologic surgeon, Dr. Jerry Brewer discussing AFx. He tells us about the risk factors, diagnosis and treatment of this rare form of skin cancer. Atypical fibroxanthoma is a skin cancer often seen in sun-exposed areas.

Atypical fibroxanthoma prognosis

The tumour-like growth should be considered a type of skin cancer but it may behave in a benign fashion. A rare type of atypical fibroxanthoma occurs in younger patients on parts of the body that are not normally overexposed to the sun. Atypical fibroxanthoma prognosis. Atypical fibroxanthoma rarely recurs after complete excision with clear margins.

AFX most commonly occurs on sun-exposed skin in elderly individuals.

The tumor presents as a single cutaneous nodule which is often ulcerated. Microscopically, it is characterized by the presence of highly atypical cytologic features, pleomorphism and abundant mitotic figures. The vast majority of patients have an excellent prognosis following conservative therapy. Recurrences are infrequent, and metastasis is rare.

AFX most commonly occurs on sun-exposed skin in elderly individuals. 2013-03-26 Atypical fibroxanthoma (AFX) was first reported by Helwig in the early 1960s . He described 20 patients with in part ulcerated tumors measuring 1–12 cm in diameter.

ATYPICAL FIBROXANTHOMA OF THE SKIN A Clinicopathologic Study of 140 Cases DAVID F. FRETZIN, MD," AND ELSON B. HELWIC, MD+ In an attempt to further understand the nature of atypical fibroxanthoma of the skin, 140 lesions were subjected to clinical, histologic, and histochemical studies.

Background: Atypical fibroxanthoma (AFX) is an uncommon, rapidly growing cutaneous neoplasm of uncertain histogenesis.

Atypical fibroxanthomas are uncommon but usually occur on the head and neck of older people.
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No. What are the symptoms of Atypical Fibroxanthoma? A weeping, or sometimes bleeding growth, or multiple lumps, may grow over a few months on the head or neck area. The lumps may be pink or red in colour. They can be ulcerated or crusted. It is not commonly painful or sore or itchy.

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The term atypical fibroxanthoma (AFX) was used in 1961 by Helwig for indicate a typically nodular ulcerative lesion arising from the sun-exposed skin of the head and neck. Rarely AFX has been described in young and in areas without evidence of actinic damage.

Atypical fibroxanthoma (AFX) is a dermal spindle-cell tumour that typically occurs on the head and neck of sun damaged older people. The tumour-like growth should be considered a type of skin cancer but it may behave in a benign fashion. Atypical fibroxanthomas are uncommon but usually occur on the head and neck of older people. They may look like other skin cancers (other than melanoma) and often appear as pink-red raised areas or bumps that do not heal and may be tender. Atypical Fibroxanthoma of the skin (AFX) is an uncommon tumor of sun-exposed areas of elderly white men, most commonly on the scalp and ears. This fibro-histiocytic spindle cell neoplasm has a potential to metastasize and behave aggressively. Diagnosis is made by immunohistochemistry.